BAX anticorps (AA 47-78)

N° du produit ABIN3030141

Cet anticorps anti-BAX est un anticorps Lapin Polyclonal détectant BAX dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour BAX anticorps (AA 47-78) (ABIN3030141)

Antigène: BAX (BCL2-Associated X Protein (BAX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAX est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BAX anticorps

Épitope: AA 47-78

Purification: Antigen affinity purified

Immunogène: This BAX antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 47-78 amino acids from the N-terminal region of human BAX.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the BAX antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the BAX antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur BAX

Antigène: BAX (BCL2-Associated X Protein (BAX))

Autre désignation: BAX

Sujet: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

UniProt: Q07812

Pathways: Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response